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Abbildung 1. Abbildung des On-Chip-Durchflusszytometers. / Figure 1: Picture of the on-chip flow cytometer. Abbildung 2: (links) Schematischer Querschnitt des Chip-Schichtstapels, der die Lichteinkopplung in den Chip, die Beleuchtung der Zellen sowie die Erfassung und Detektion der Zellstreusignale zeigt. (rechts) Experimentelles Streudiagramm einer vollständigen mononukleären Probe aus peripherem Blut, gemessen mit dem On-Chip-Durchflusszytometer. / Figure 2: (Left) Schematic cross-section of the chip layer stack, indicating light coupling into the chip, cell illumination, and collection and detection of cell scattering signals. (Right) Experimental scatter plot of a full peripheral blood mononuclear sample measured with the on-chip flow cytometer.
  • Science

On-chip flow cytometer using integrated photonics paves the way for high-throughput cell analysis

Imec and Sarcura introduce scalable on-chip detection of human white blood cells

Imec, a world-leading research and innovation hub in nanoelectronics and digital technologies, and Sarcura GmbH, an Austrian early-stage technology start-up, present their proof-of-concept on-chip flow cytometer using integrated photonics. Published on 20th May 2024 in Scientific Reports, part of th…

Gemeinsam untersuchen Forschende des Fraunhofer ITEM, des Fraunhofer IWS und der Universität Regensburg die Metastasierung von Tumorzellen in mikrophysiologischen Systemen. © minkus-images.de/Fraunhofer IWS / Researchers from Fraunhofer ITEM, Fraunhofer IWS, and the University of Regensburg are jointly investigating the growth of tumor cells in microphysiological systems. © minkus-images.de/Fraunhofer IWS Bereits seit mehreren Jahren entwickelt das Fraunhofer IWS mikrophysiologische Systeme in der Größe einer Tablettenschachtel. Nun ist es möglich, bis zu zehn Gewebeschnitte auf einem Chip zu kultivieren. © minkus-images.de/Fraunhofer IWS / Fraunhofer IWS has been developing microphysiological systems the size of a box of tablets for several years. Cultivating up to ten tissue slices on one chip is now possible. © minkus-images.de/Fraunhofer IWS Um herauszufinden, wie sich Krebszellen entwickeln und im Körper verbreiten, wollen die Forschungspartner die Umgebungsbedingungen in Zukunft noch effektiver in den Mikrosystemen nachbilden. © minkus-images.de/Fraunhofer IWS / In order to find out how cancer cells develop and spread in the body, the research partners want to simulate the environmental conditions in the microsystems even more effectively in the future. © minkus-images.de/Fraunhofer IWS Neben Krebs lassen sich auch andere Erkrankungen wie die Fibrose an Gewebeschnitten in mikrophysiologischen Systemen untersuchen. Daran arbeiten Wissenschaftlerinnen und Wissenschaftler des Fraunhofer IWS und des Fraunhofer ITEM gemeinsam im Projekt FIBROPATHS. © minkus-images.de/Fraunhofer IWS / In addition to cancer, other diseases, such as fibrosis, can also be examined on tissue sections in microphysiological systems. Scientists from Fraunhofer IWS and Fraunhofer ITEM are working on this together within the FIBROPATHS project. © minkus-images.de/Fraunhofer IWS
  • Products, devices, systems, plants for applications

Fraunhofer IWS Develops Microphysiological Systems for Cultivation of Tumor Tissue Sections in Joint Effort

New Opportunity for Cancer Therapy: Miniature Lab Provides Insights into Metastases Development

Every year, around half a million people in Germany are diagnosed with cancer. Despite the existence of effective treatment options for many types of cancer, many questions about the development of the disease remain unanswered. Why does a tumor develop? What factors promote the growth of cancer cel…

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