Optimization of the room air current in complex clean-room systems with FLOVENT V6.1

The Flomerics Group is the market leader of CFD simulation and analysis software for thermal and flowtechnical applications. Particularly in complex clean-room systems certain requirements within the range of the room air current can be analyzed and evaluated only with the help of the numeric simulation.- simulation and analysis of clean-room systems for the operating conditions as built, RK remainder and operational - investigation of demarcation concepts: Displacement, differential pressure - simulation of the controlled air flow, with low turbulences displacement ventilation LF (laminar flow) - simulation relationship around/outside air - simulation of Erholzeiten/Clean UP concerning contamination and concentration - simulation of the figures of air changes - proof and recording of air flow pictures - optimization of the room air guidance within the range of pure productions - studies for climatic/ventilation concepts, virtual Smoke Studies - simulation of pressure, concentration, temperature and air flow in air-locks and autoclaves FLOVENT of reference projects Merck KGaA, bioMérieux, GlaxoSmithKline, HNC, Alcon Belgium, SGS Thomson,Cousin Pharma manufacturing GmbH & CO kg of description of the project bioMérieux - analysis and optimization of the room air current within the filling up ranges of the pure areas experts in the diagnosis of infections - succeeded it over an analysis of the air flows within the filling up ranges of its pure areas with the help of the software to Flovent - to eliminate the risk of impurities completely. The simulation of the air flows had resulted in that the danger of mutual impurities can be perfectly excluded by slight changes at the plastic curtains by the pure areas bioMérieux could in such a way in shortest time the most economical solution find, in order to reduce the risk of mutual impurities the throughput of the machines to filling the glasflaeschchen to increase and still completely substantially time and money to save.bioMérieux develops and produces reagents and automatic devices for medical analyses, which are used also in the Kosmetikproduktion as well as with quality control in the pharmaceutical and the foodstuffs industry. In the tendency to reduce the risk of impurities of their products one had decided with bioMérieux to examine the air flows in the pure areas in order to point the present restrictions out, before changes were tackled for the increase of the throughput. The first simulation with Flovent was undertaken at an individual machine to filling small glasflaeschchen. Here one was limited to two possible sources for impurities transferred by air. At the beginning the operators of the machine and its influence on the rack machine were examined with the help of the software. On this rack machine two persons work.The machine is under a mechanism, which produces a luftschleier (LF). Flexible plastic curtains around the machine provide for an environment without impurities. The simulation pointed clearly two ranges, in which air back-flowed, in each case to both sides of the operators. Here the danger of impurities existed by the fact that exhaust air was back-pushed into the flow of fresh air. In order to pursue the possible propagation of this pollution, sources at the hands of the operators, at their faces and at the pump of the rack machine were added. One had already recognized these ranges with bioMérieux in the past as sources for impurities. That the impurities, which proceeded from the hands of the operators were exhausted problem-free by the air flow, the impurities of the pump pointed themselves however to the fresh air arrived. A second analysis was made at a filling up area with two machines.Each machine was equipped with their own luftschleier, plastic curtains as well as separate and exhaust air ducts. The pure area was in such a way laid out that the machines could be operated independently and if necessary even with different products. Here it concerned with priority to find out whether with such an enterprise the danger of mutual pollution of the two products existed over the ambient air. The Flovent simulation resulted in a small however quantifiable exchange between the two ventilation systems. Particles of a separated range were transported in each case into that different one, and there was so the danger of a mutual pollution. Changes in the Flovent simulation showed in both cases that the simplest and most economical solution could be caused for the prevention of these impurities by a changed arrangement of the plastic curtains.Without analyzing the simulation with Flovent would have been impossible it for bioMérieux, the range so fast and to the same costs and to determine the necessary changes. Detailed information to our products and services receives you also under 0049 (0)711 77915 50 Flomerics Ltd. Niederlassung Germany partner: Torsten Jaeschke, dipl. Ing.