Additive Manufacturing in the throes of technological change

Additive Manufacturing, particularly metal 3D printing, has evolved from a promising technology to a serious constituent of industrial production. Industries such as plant engineering, aerospace, automotive and metalworking are facing a technological transformation that could have far-reaching impli…

Aktin gefärbter 3T3 Fibroblastensphäroid für den LIFT-Transfer, kultiviert in lasergefertigten Mikronäpfchen. © Fraunhofer ILT, Aachen / Actin-stained 3T3 fibroblast spheroid for LIFT transfer, cultivated in laser-fabricated microwells. © Fraunhofer ILT, Aachen, Germany

Das LIFTOSCOPE vereint Hochgeschwindigkeits-mikroskopie, KI-Analyse und Lokalisation lebender Zellen und Zellverbände mit dem laserinduzierten Vorwärts-Transfer (LIFT). Der Laserstrahl wird über Spiegel direkt in den Strahlengang des Mikroskops eingekoppelt. Anwender können zwischen Kamerabeobachtung und LIFT-Prozess wechseln. © Fraunhofer ILT, Aachen / The LIFTOSCOPE combines high-speed microscopy, AI-based analysis and localization of living cells and cell clusters with laser-induced forward transfer (LIFT). The laser is coupled directly into the beam path of the microscope via mirrors. Users can switch between camera observation and the LIFT process. © Fraunhofer ILT, Aachen, Germany

Das MIR LIFT-Verfahren transferiert lebende Zellen mit hoher Rate von bis zu 100 Hz nacheinander auf Mikrotiterplatten (MTP). Um den hocheffizienten Prozess herstellerunabhängig in Mikroskopie-Plattformen integrieren zu können, hat das Fraunhofer ILT u.a. die abgebildete Halterung für eine 6-Well-MTP entwickelt. © Fraunhofer ILT, Aachen / The MIR LIFT process transfers living cells to microtiter plates (MTP) one after the other at a high rate of up to 100 Hz. In order to integrate the highly efficient process into microscopy platforms regardless of the manufacturer, Fraunhofer ILT has developed, among other things, the holder shown here for a six-well MTP. © Fraunhofer ILT, Aachen, Germany

Forschende des Fraunhofer ILT erproben das LIFTOSCOPE für die KI-gestützte, vollautomatisierte Hochdurchsatzsortierung lebender Zellen mit gepulster Laserstrahlung. © Fraunhofer ILT, Aachen / Researchers at Fraunhofer ILT are testing the LIFTOSCOPE for AI-assisted, fully automated high-throughput sorting of living cells by pulsed laser radiation. © Fraunhofer ILT, Aachen, Germany

13.06.2024
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Lasertechnology

Automated high-throughput sorting of living cells using laser light and AI

Tests on living cell cultures are becoming increasingly important for personalized medicine, drug development and clinical research. The Aachen-based Fraunhofer Institutes for Laser Technology ILT and for Production Technology IPT have developed an AI-assisted high-throughput process that now makes…

Internationales Forscherteam des Lawrence Livermore National Laboratory, des Fraunhofer ILT und der ELI - Extreme Light Infrastructure in der ELI Beamlines Facility, Prag, Tschechische Republik. © ELI ERIC / International team of researchers from Lawrence Livermore National Laboratory, Fraunhofer ILT and ELI - Extreme Light Infrastructure at the ELI Beamlines Facility, Prague, Czech Republic. © ELI ERIC

11.06.2024
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Products, devices, systems, plants for applications

Harnessing Machine Learning for Breakthroughs with High-Power Lasers

A team of international scientists from Lawrence Livermore National Laboratory (LLNL), Fraunhofer Institute for Laser Technology ILT, and the Extreme Light Infrastructure (ELI) collaborated on an experiment to optimise high-intensity high-repetition rate laser technology using machine learning. The…

Im Harzbad gefertigtes Musterbauteil aus der HoPro-3D-Anlage. © Fraunhofer ILT, Aachen. / Sample component produced in a resin bath from the HoPro3D system. © Fraunhofer ILT, Aachen, Germany.

Laboranlage zur Erprobung des Kombinationsprozesses. © Fraunhofer ILT, Aachen. / Laboratory plant for testing the combination process. © Fraunhofer ILT, Aachen, Germany.

Realisierung von MPP- und DLP-Prozess in einem Harzbad. © Fraunhofer ILT, Aachen. / Realization of MPP and DLP process in one resin bath. © Fraunhofer ILT, Aachen, Germany.

07.12.2022
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Science

Combined and efficient: Two steps to the goal

Together with industrial partners, the Fraunhofer Institute for Laser Technology ILT has developed a novel system for producing high-resolution microcomponents by photo-crosslinking. Thanks to their work in the project “High productivity and detail accuracy in additive manufacturing by combining U…

Parallele, kontinuierliche Perfusion von vier Organ-on-Chip Systemen. © Fraunhofer ILT, Aachen / Parallel, continuous perfusion of four organ-on-chip systems. © Fraunhofer ILT, Aachen, Germany

27.05.2022
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Lasertechnology

Process Chains for Isolation and Analysis: from Single Cells to Organoids

Researchers at the Fraunhofer Institute for Laser Technology ILT are working on new tools for the preparation and analysis of single cells and cell assemblies. The team developed the “Liftoscope,” a system for cell sorting for subsequent cultivation that can analyze and transfer biomaterials pre…

Der Greifarm – das zentrale Werkzeug für die hochpräzise Justage der Weltraumkomponenten - besteht aus einem statischen und einem beweglichen Teil. © Fraunhofer ILT, Aachen. / The gripper arm – the central tool for the high-precision alignment of space components – consists of a static and a moving part. © Fraunhofer ILT, Aachen, Germany.

Künstlerische Darstellung des MERLIN Instruments auf Basis der Myriade- Satellitenplattform. © CNES/illustration David DUCROS, 2016. / An artist's impression of the MERLIN instrument based on the Myriad satellite platform. © CNES/illustration David DUCROS, 2016.

17.09.2021
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3D printing

Gripper Arm from the 3D Printer for Assembling Optical Systems with Maximum Precision

The Fraunhofer Institute for Laser Technology ILT in Aachen has been developing and building laser systems for use in space for several years. At the same time, the Aachen scientists are also researching technologies for metallic 3D printing. Using the Laser Powder Bed Fusion (LPBF) process, Fraunho…

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